Anti-DKK2 Antibody

Catalog number M06431-01

Discontinued

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About this product

Boster Bio Anti-DKK2 Antibody (Catalog # M06431) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number: M06431-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity) .
Synonyms: Dickkopf-related protein 2, Dickkopf-2, Dkk-2, hDkk-2, DKK2
Gene Name: DKK2
UniProt: Q9UBU2
Host: Mouse
Reactivity: Human, Mouse
Immunogen: This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.
Clonality: Monoclonal
Clone: Clone: 1833CT856.7.20
Tissue Specificity: Expressed in heart, brain, skeletal muscle and lung
Applications: WB
Field of Research: Stem Cells, Anti-Wnt-Pathway (plus Lgr5) Antibodies
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution: WB: 1:2000
Function: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity) .
Molecular Weight: 28447 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: IgG1, k
Subcellular Location: Secreted.

Frequently Asked Questions

What is the catalog number for Anti-DKK2 Antibody?

The catalog number for Anti-DKK2 Antibody is M06431.

Is Anti-DKK2 Antibody in stock?

Anti-DKK2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-DKK2 Antibody?

The safety data sheet for Anti-DKK2 Antibody is available here: https://www.bosterbio.com/msds?sku=M06431.

What is Anti-DKK2 Antibody used for?

Boster Bio Anti-DKK2 Antibody (Catalog # M06431) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.