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Product details

Anti-TGFB1 Antibody

Catalog number A00019-1-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-TGFB1 Antibody (Catalog # A00019-1) . Tested in WB application (s) . This antibody reacts with Human, Rat.

Specifications

Catalog number
A00019-1-01
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Synonyms
Transforming growth factor beta-1, TGF-beta-1, Latency-associated peptide, LAP, TGFB1, TGFB
Gene Name
TGFB1
UniProt
P01137
Host
Rabbit
Reactivity
Human, Rat
Immunogen
This TGFB1 antibody is generated from a rabbit immunized with a recombinant protein of human TGFB1.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in bone (PubMed:11746498, PubMed:17827158) . Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA) (PubMed:11746498, PubMed:17827158) . Colocalizes with ASPN in chondrocytes within OA lesions of articular cartilage (PubMed:17827158)
Applications
WB
Field of Research
Cancer, Cardiovascular, Developmental Biology, Metabolism, Signal Transduction, Stem Cells, Cytokines
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:2000
Function
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
Molecular Weight
44341 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix

Frequently Asked Questions

What is the catalog number for Anti-TGFB1 Antibody?

The catalog number for Anti-TGFB1 Antibody is A00019-1.

Is Anti-TGFB1 Antibody in stock?

Anti-TGFB1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-TGFB1 Antibody?

The safety data sheet for Anti-TGFB1 Antibody is available here: https://www.bosterbio.com/msds?sku=A00019-1.

What is Anti-TGFB1 Antibody used for?

Boster Bio Anti-TGFB1 Antibody (Catalog # A00019-1) . Tested in WB application (s) . This antibody reacts with Human, Rat.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

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