Anti-CAD Antibody (Center) — image 1 of 2

Product details

Anti-CAD Antibody (Center)

Catalog number A00463-3-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-CAD Antibody (Center) (Catalog # A00463-3) . Tested in WB, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number: A00463-3-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
Synonyms: CAD protein, Glutamine-dependent carbamoyl-phosphate synthase, Aspartate carbamoyltransferase, Dihydroorotase, CAD
Gene Name: CAD
UniProt: P27708
Host: Rabbit
Reactivity: Human
Immunogen: This CAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-809 amino acids from the Central region of human CAD.
Clonality: Polyclonal
Applications: WB, IHC-P, Flow Cytometry
Field of Research: Cell Biology, Metabolism
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) .
Molecular Weight: 242984 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Cytoplasm. Nucleus. Note=Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth
Prediction Reactivity: Mouse

Frequently Asked Questions

What is the catalog number for Anti-CAD Antibody (Center)?

The catalog number for Anti-CAD Antibody (Center) is A00463-3.

Is Anti-CAD Antibody (Center) in stock?

Anti-CAD Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CAD Antibody (Center)?

The safety data sheet for Anti-CAD Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A00463-3.

What is Anti-CAD Antibody (Center) used for?

Boster Bio Anti-CAD Antibody (Center) (Catalog # A00463-3) . Tested in WB, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.