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Product details

Anti-Activin Receptor Type IA (ACVR1) Antibody (Center R147)

Catalog number A00798-2-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-Activin Receptor Type IA (ACVR1) Antibody (Center R147) (Catalog # A00798-2) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number
A00798-2-01
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors.
Synonyms
Activin receptor type-1, Activin receptor type I, ACTR-I, Activin receptor-like kinase 2, ALK-2, Serine/threonine-protein kinase receptor R1, SKR1, TGF-B superfamily receptor type I, TSR-I, ACVR1, ACVRLK2
Gene Name
ACVR1
UniProt
Q04771
Host
Rabbit
Reactivity
Human
Immunogen
This Activin Receptor Type IA (ACVR1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-162 amino acids from the Central region of human Activin Receptor Type IA (ACVR1) .
Clonality
Polyclonal
Tissue Specificity
Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells
Applications
WB, IHC-P
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
20628059229772371791140125354296974822817911401
Molecular Weight
57153 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
Membrane; Single-pass type I membrane protein.
Prediction Reactivity
Bovine, Mouse, Rat

Frequently Asked Questions

What is the catalog number for Anti-Activin Receptor Type IA (ACVR1) Antibody (Center R147)?

The catalog number for Anti-Activin Receptor Type IA (ACVR1) Antibody (Center R147) is A00798-2.

Is Anti-Activin Receptor Type IA (ACVR1) Antibody (Center R147) in stock?

Anti-Activin Receptor Type IA (ACVR1) Antibody (Center R147) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Activin Receptor Type IA (ACVR1) Antibody (Center R147)?

The safety data sheet for Anti-Activin Receptor Type IA (ACVR1) Antibody (Center R147) is available here: https://www.bosterbio.com/msds?sku=A00798-2.

What is Anti-Activin Receptor Type IA (ACVR1) Antibody (Center R147) used for?

Boster Bio Anti-Activin Receptor Type IA (ACVR1) Antibody (Center R147) (Catalog # A00798-2) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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