Anti-PLA2G4A Antibody (Center)

Catalog number A00854-1-01

Discontinued

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About this product

Boster Bio Anti-PLA2G4A Antibody (Center) (Catalog # A00854-1) . Tested in WB, Flow Cytometry, IF, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: A00854-1-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca (2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
Synonyms: Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA, Phospholipase A2, Phosphatidylcholine 2-acylhydrolase, Lysophospholipase, PLA2G4A, CPLA2, PLA2G4
Gene Name: PLA2G4A
UniProt: P47712
Host: Rabbit
Reactivity: Human
Immunogen: This PLA2G4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-541 amino acids from the Central region of human PLA2G4A.
Clonality: Polyclonal
Tissue Specificity: Expressed in various cells and tissues such as macrophages, neutrophils, fibroblasts and lung endothelium. Expressed in platelets (at protein level) (PubMed:25102815)
Applications: WB, Flow Cytometry, IF, IHC-P
Field of Research: Cardiovascular, Immunology, Metabolism, Signal Transduction, Inflammation
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: 779489186199918702602942512110358058147095601661705917472963276420671845199377948918619991942512110358058174729631845199318451993779489194251211035805817472963276420677794891126728057794891
Molecular Weight: 85239 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Cytoplasm. Golgi apparatus membrane. Nucleus envelope Note=Translocates to intracellular membranes in a calcium-dependent way.
Prediction Reactivity: Chicken, Zebrafish, Horse, Mouse, Rabbit, Rat

Frequently Asked Questions

What is the catalog number for Anti-PLA2G4A Antibody (Center)?

The catalog number for Anti-PLA2G4A Antibody (Center) is A00854-1.

Is Anti-PLA2G4A Antibody (Center) in stock?

Anti-PLA2G4A Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PLA2G4A Antibody (Center)?

The safety data sheet for Anti-PLA2G4A Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A00854-1.

What is Anti-PLA2G4A Antibody (Center) used for?

Boster Bio Anti-PLA2G4A Antibody (Center) (Catalog # A00854-1) . Tested in WB, Flow Cytometry, IF, IHC-P application (s) . This antibody reacts with Human.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.