Anti-PPARD Antibody (C-term)

Catalog number A01557-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-PPARD Antibody (C-term) (Catalog # A01557) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A01557-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants.
Synonyms: Peroxisome proliferator-activated receptor delta, PPAR-delta, NUCI, Nuclear hormone receptor 1, NUC1, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferator-activated receptor beta, PPAR-beta, PPARD, NR1C2, PPARB
Gene Name: PPARD
UniProt: Q03181
Host: Rabbit
Reactivity: Human
Immunogen: This PPARD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human PPARD.
Clonality: Polyclonal
Tissue Specificity: Ubiquitous with maximal levels in placenta and skeletal muscle
Applications: WB
Field of Research: Cardiovascular, Metabolism, Anti-Wnt-Pathway (plus Lgr5) Antibodies
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution: WB: 1:1000
Function: 35675826
Molecular Weight: 49903 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Nucleus.

Frequently Asked Questions

What is the catalog number for Anti-PPARD Antibody (C-term)?

The catalog number for Anti-PPARD Antibody (C-term) is A01557.

Is Anti-PPARD Antibody (C-term) in stock?

Anti-PPARD Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PPARD Antibody (C-term)?

The safety data sheet for Anti-PPARD Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A01557.

What is Anti-PPARD Antibody (C-term) used for?

Boster Bio Anti-PPARD Antibody (C-term) (Catalog # A01557) . Tested in WB application (s) . This antibody reacts with Human.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.