Anti-DIO2 Antibody (Center) — image 1 of 5

Product details

Anti-DIO2 Antibody (Center)

Catalog number A02249-1-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-DIO2 Antibody (Center) (Catalog # A02249-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number: A02249-1-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: DIO2 belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3) .
Synonyms: Type II iodothyronine deiodinase, 5DII, DIOII, Type 2 DI, Type-II 5'-deiodinase, DIO2, ITDI2, TXDI2
Gene Name: DIO2
UniProt: Q92813
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: This DIO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids of human DIO2.
Clonality: Polyclonal
Tissue Specificity: Isoform 1 is expressed in the lung, trachea, kidney, heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain (PubMed:8755651, PubMed:11165050) . Isoform 2 is expressed in the brain, heart, kidney and trachea (PubMed:11165050)
Applications: WB, Flow Cytometry, IHC-P
Field of Research: Cancer, Metabolism, Neuroscience, Signal Transduction
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) . Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Molecular Weight: 30552 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Membrane; Single-pass membrane protein
Prediction Reactivity: Pig

Frequently Asked Questions

What is the catalog number for Anti-DIO2 Antibody (Center)?

The catalog number for Anti-DIO2 Antibody (Center) is A02249-1.

Is Anti-DIO2 Antibody (Center) in stock?

Anti-DIO2 Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-DIO2 Antibody (Center)?

The safety data sheet for Anti-DIO2 Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A02249-1.

What is Anti-DIO2 Antibody (Center) used for?

Boster Bio Anti-DIO2 Antibody (Center) (Catalog # A02249-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human, Mouse.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.