Anti-TLE1 Antibody (N-term) — image 1 of 2

Product details

Anti-TLE1 Antibody (N-term)

Catalog number A02460-1-01

Discontinued

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About this product

Boster Bio Anti-TLE1 Antibody (N-term) (Catalog # A02460-1) . Tested in IF, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A02460-1-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Synonyms: Transducin-like enhancer protein 1, E (Sp1) homolog, Enhancer of split groucho-like protein 1, ESG1, TLE1
Gene Name: TLE1
UniProt: Q04724
Host: Rabbit
Reactivity: Human
Immunogen: This TLE1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 187-221 amino acids from the N-terminal region of human TLE1.
Clonality: Polyclonal
Tissue Specificity: In all tissues examined, mostly in brain, liver and muscle
Applications: IF, WB
Field of Research: Signal Transduction, Stem Cells, Anti-Wnt-Pathway (plus Lgr5) Antibodies
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF- 1- and HES1-mediated transcriptional repression (By similarity) . The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Molecular Weight: 83201 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Nucleus. Note=Nuclear and chromatin-associated, depending on isoforms and phosphorylation status. Hyperphosphorylation decreases the affinity for nuclear components

Frequently Asked Questions

What is the catalog number for Anti-TLE1 Antibody (N-term)?

The catalog number for Anti-TLE1 Antibody (N-term) is A02460-1.

Is Anti-TLE1 Antibody (N-term) in stock?

Anti-TLE1 Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-TLE1 Antibody (N-term)?

The safety data sheet for Anti-TLE1 Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=A02460-1.

What is Anti-TLE1 Antibody (N-term) used for?

Boster Bio Anti-TLE1 Antibody (N-term) (Catalog # A02460-1) . Tested in IF, WB application (s) . This antibody reacts with Human.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.