Anti-EBP1 Antibody (C-term) — image 1 of 4

Product details

Anti-EBP1 Antibody (C-term)

Catalog number A02791-2-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-EBP1 Antibody (C-term) (Catalog # A02791-2) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number: A02791-2-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.
Synonyms: Proliferation-associated protein 2G4, Cell cycle protein p38-2G4 homolog, hG4-1, ErbB3-binding protein 1, PA2G4, EBP1
Gene Name: PA2G4
UniProt: Q9UQ80
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: This EBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the C-terminal region of human EBP1.
Clonality: Polyclonal
Tissue Specificity: Isoform 2 is undetectable whereas isoform 1 is strongly expressed in cancer cells (at protein level) . Isoform 1 and isoform 2 are widely expressed, including heart, brain, lung, pancreas, skeletal muscle, kidney, placenta and liver
Applications: WB, Flow Cytometry, IHC-P
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function: May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG) . Inhibits transcription of some E2F1- regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap- independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity) . Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity) .
Molecular Weight: 43787 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: [Isoform 1]: Cytoplasm. Nucleus, nucleolus Note=Translocates to the nucleus upon treatment with HRG Phosphorylation at Ser-361 by PKC/PRKCD regulates its nucleolar localization.
Prediction Reactivity: Rat

Frequently Asked Questions

What is the catalog number for Anti-EBP1 Antibody (C-term)?

The catalog number for Anti-EBP1 Antibody (C-term) is A02791-2.

Is Anti-EBP1 Antibody (C-term) in stock?

Anti-EBP1 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-EBP1 Antibody (C-term)?

The safety data sheet for Anti-EBP1 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A02791-2.

What is Anti-EBP1 Antibody (C-term) used for?

Boster Bio Anti-EBP1 Antibody (C-term) (Catalog # A02791-2) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human, Mouse.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.