Anti-OASL Antibody (C-term)

Catalog number A04123-1-01

Discontinued

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About this product

Boster Bio Anti-OASL Antibody (C-term) (Catalog # A04123-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: A04123-1-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: 2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
Synonyms: 2'-5'-oligoadenylate synthase-like protein, 2'-5'-OAS-related protein, 2'-5'-OAS-RP, 59 kDa 2'-5'-oligoadenylate synthase-like protein, Thyroid receptor-interacting protein 14, TR-interacting protein 14, TRIP-14, p59 OASL, p59OASL, OASL, TRIP14
Gene Name: OASL
UniProt: Q15646
Host: Rabbit
Reactivity: Human
Immunogen: This OASL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-514 amino acids from the C-terminal region of human OASL.
Clonality: Polyclonal
Tissue Specificity: Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis
Applications: WB, IHC-P
Field of Research: Cell Biology, Immunology, Antiviral Signaling, Innate Immunity
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function: Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
Molecular Weight: 59226 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: [Isoform p56]: Nucleus, nucleolus. Cytoplasm.

Frequently Asked Questions

What is the catalog number for Anti-OASL Antibody (C-term)?

The catalog number for Anti-OASL Antibody (C-term) is A04123-1.

Is Anti-OASL Antibody (C-term) in stock?

Anti-OASL Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-OASL Antibody (C-term)?

The safety data sheet for Anti-OASL Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A04123-1.

What is Anti-OASL Antibody (C-term) used for?

Boster Bio Anti-OASL Antibody (C-term) (Catalog # A04123-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.