Anti-HMGCS2 Antibody (C-term)

Catalog number A04371-1-01

Discontinued

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About this product

Boster Bio Anti-HMGCS2 Antibody (C-term) (Catalog # A04371-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: A04371-1-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: HMGCS2 belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting.
Synonyms: Hydroxymethylglutaryl-CoA synthase, mitochondrial, HMG-CoA synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, HMGCS2
Gene Name: HMGCS2
UniProt: P54868
Host: Rabbit
Reactivity: Human
Immunogen: This HMGCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-508 amino acids from the C-terminal region of human HMGCS2.
Clonality: Polyclonal
Tissue Specificity: Expression in liver is 200-fold higher than in any other tissue. Low expression in colon, kidney, testis, and pancreas Very low expression in heart and skeletal muscle (PubMed:7893153, PubMed:21952825, PubMed:16940161) . Not detected in brain (PubMed:21952825) .
Applications: WB, Flow Cytometry, IHC-P
Field of Research: Cancer, Cardiovascular, Metabolism, Signal Transduction, Mitochondria
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function: Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate.
Molecular Weight: 56635 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Mitochondrion {ECO:0000250|UniProtKB:P22791}.

Frequently Asked Questions

What is the catalog number for Anti-HMGCS2 Antibody (C-term)?

The catalog number for Anti-HMGCS2 Antibody (C-term) is A04371-1.

Is Anti-HMGCS2 Antibody (C-term) in stock?

Anti-HMGCS2 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-HMGCS2 Antibody (C-term)?

The safety data sheet for Anti-HMGCS2 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A04371-1.

What is Anti-HMGCS2 Antibody (C-term) used for?

Boster Bio Anti-HMGCS2 Antibody (C-term) (Catalog # A04371-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.