Anti-UIMC1 Antibody (C-term)

Catalog number A06262-2-01

Discontinued

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for A06262-2-01

Size / count 80 µL

This variant is discontinued and cannot be added to your cart. Select another variant to view its availability.

About this product

Boster Bio Anti-UIMC1 Antibody (C-term) (Catalog # A06262-2) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A06262-2-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs) . The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. Also weakly binds monoubiquitin but with much less affinity than 'Lys-63'-linked ubiquitin. May interact with monoubiquitinated histones H2A and H2B; the relevance of such results is however unclear in vivo. Does not bind Lys-48'-linked ubiquitin. May indirectly act as a transcriptional repressor by inhibiting the interaction of NR6A1 with the corepressor NCOR1.
Synonyms: BRCA1-A complex subunit RAP80, Receptor-associated protein 80, Retinoid X receptor-interacting protein 110, Ubiquitin interaction motif-containing protein 1, UIMC1, RAP80, RXRIP110
Gene Name: UIMC1
UniProt: Q96RL1
Host: Rabbit
Reactivity: Human
Immunogen: This UIMC1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 567-601 amino acids from the C-terminal region of human UIMC1.
Clonality: Polyclonal
Tissue Specificity: Expressed in testis, ovary, thymus and heart. Expressed in germ cells of the testis.
Applications: Flow Cytometry, WB
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: 2462747219328070
Molecular Weight: 79727 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs)

Frequently Asked Questions

What is the catalog number for Anti-UIMC1 Antibody (C-term)?

The catalog number for Anti-UIMC1 Antibody (C-term) is A06262-2.

Is Anti-UIMC1 Antibody (C-term) in stock?

Anti-UIMC1 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-UIMC1 Antibody (C-term)?

The safety data sheet for Anti-UIMC1 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A06262-2.

What is Anti-UIMC1 Antibody (C-term) used for?

Boster Bio Anti-UIMC1 Antibody (C-term) (Catalog # A06262-2) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.