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Product details

Anti-GPM6A Antibody (C-term)

Catalog number A06295-1-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-GPM6A Antibody (C-term) (Catalog # A06295-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number
A06295-1-01
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Synonyms
Neuronal membrane glycoprotein M6-a, M6a, GPM6A, M6A
Gene Name
GPM6A
UniProt
P51674
Host
Rabbit
Reactivity
Human
Immunogen
This GPM6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-259 amino acids from the C-terminal region of human GPM6A.
Clonality
Polyclonal
Applications
WB, Flow Cytometry
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca (2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs) ; enhances internalization and recycling of mu-type opioid receptor.
Molecular Weight
31210 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
Cell membrane {ECO:0000250|UniProtKB:P35802}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P35802}. Cell projection, axon {ECO:0000250|UniProtKB:P35802}. Cell projection, growth cone {ECO:0000250|UniProtKB:P35802}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q812E9}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q812E9}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q812E9}. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons (By similarity) . Localized to the growth cone edge membrane of elongating axons (By similarity) {ECO:0000250|UniProtKB:P35802, ECO:0000250|UniProtKB:Q812E9}
Prediction Reactivity
Bovine, Mouse, Rat

Frequently Asked Questions

What is the catalog number for Anti-GPM6A Antibody (C-term)?

The catalog number for Anti-GPM6A Antibody (C-term) is A06295-1.

Is Anti-GPM6A Antibody (C-term) in stock?

Anti-GPM6A Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-GPM6A Antibody (C-term)?

The safety data sheet for Anti-GPM6A Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A06295-1.

What is Anti-GPM6A Antibody (C-term) used for?

Boster Bio Anti-GPM6A Antibody (C-term) (Catalog # A06295-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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