Anti-CIR Antibody (N-term)

Catalog number A07268-01

Discontinued

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for A07268-01

Size / count 80 µL

This variant is discontinued and cannot be added to your cart. Select another variant to view its availability.

About this product

Boster Bio Anti-CIR Antibody (N-term) (Catalog # A07268) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A07268-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: CIR may modulate splice site selection during alternative splicing of pre-mRNAs. It fegulates transcription and acts as corepressor for RBPSUH. It recruits RBPSUH to the Sin3-histone deacetylase complex (HDAC) and is required for RBPSUH-mediated repression of transcription.
Synonyms: Corepressor interacting with RBPJ 1, CBF1-interacting corepressor, Recepin, CIR1, CIR
Gene Name: CIR1
UniProt: Q86X95
Host: Rabbit
Reactivity: Human
Immunogen: This CIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human CIR.
Clonality: Polyclonal
Tissue Specificity: Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas.
Applications: WB
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution: WB: 1:1000
Function: May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity) . Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC) . Required for RBPJ-mediated repression of transcription.
Molecular Weight: 52313 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome

Frequently Asked Questions

What is the catalog number for Anti-CIR Antibody (N-term)?

The catalog number for Anti-CIR Antibody (N-term) is A07268.

Is Anti-CIR Antibody (N-term) in stock?

Anti-CIR Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CIR Antibody (N-term)?

The safety data sheet for Anti-CIR Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=A07268.

What is Anti-CIR Antibody (N-term) used for?

Boster Bio Anti-CIR Antibody (N-term) (Catalog # A07268) . Tested in WB application (s) . This antibody reacts with Human.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

All Products