Anti-HSD17B12 Antibody (Center)

Catalog number A07397-1-01

Discontinued

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About this product

Boster Bio Anti-HSD17B12 Antibody (Center) (Catalog # A07397-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: A07397-1-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA during the second step of fatty acid elongation.
Synonyms: Estradiol 17-beta-dehydrogenase 12, 17-beta-hydroxysteroid dehydrogenase 12, 17-beta-HSD 12, 3-ketoacyl-CoA reductase, KAR, 131-, HSD17B12
Gene Name: HSD17B12
UniProt: Q53GQ0
Host: Rabbit
Reactivity: Human
Immunogen: This HSD17B12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the Central region of human HSD17B12.
Clonality: Polyclonal
Tissue Specificity: Expressed in most tissues tested. Highly expressed in the ovary and mammary. Expressed in platelets
Applications: WB, Flow Cytometry, IHC-P
Field of Research: Cell Biology, Metabolism, Signal Transduction
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3- hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.
Molecular Weight: 34324 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Prediction Reactivity: Monkey

Frequently Asked Questions

What is the catalog number for Anti-HSD17B12 Antibody (Center)?

The catalog number for Anti-HSD17B12 Antibody (Center) is A07397-1.

Is Anti-HSD17B12 Antibody (Center) in stock?

Anti-HSD17B12 Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-HSD17B12 Antibody (Center)?

The safety data sheet for Anti-HSD17B12 Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A07397-1.

What is Anti-HSD17B12 Antibody (Center) used for?

Boster Bio Anti-HSD17B12 Antibody (Center) (Catalog # A07397-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.