Anti-PCGF1 Antibody (Center)

Catalog number A08147-01

Discontinued

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About this product

Boster Bio Anti-PCGF1 Antibody (Center) (Catalog # A08147) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A08147-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin- dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element) . Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down- regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Synonyms: Polycomb group RING finger protein 1, Nervous system Polycomb-1, NSPc1, RING finger protein 68, PCGF1, NSPC1, RNF68
Gene Name: PCGF1
UniProt: Q9BSM1
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: This PCGF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 117-151 amino acids from the Central region of human PCGF1.
Clonality: Polyclonal
Tissue Specificity: Ubiquitous.
Applications: WB
Field of Research: Cancer, Cell Biology
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution: WB: 1:1000
Function: 261513322615133226687479
Molecular Weight: 30346 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Nucleus
Prediction Reactivity: Bovine

Frequently Asked Questions

What is the catalog number for Anti-PCGF1 Antibody (Center)?

The catalog number for Anti-PCGF1 Antibody (Center) is A08147.

Is Anti-PCGF1 Antibody (Center) in stock?

Anti-PCGF1 Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PCGF1 Antibody (Center)?

The safety data sheet for Anti-PCGF1 Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A08147.

What is Anti-PCGF1 Antibody (Center) used for?

Boster Bio Anti-PCGF1 Antibody (Center) (Catalog # A08147) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.