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Product details

Anti-LMCD1 Antibody (C-term)

Catalog number A08888-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-LMCD1 Antibody (C-term) (Catalog # A08888) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
A08888-01
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity) . Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Synonyms
LIM and cysteine-rich domains protein 1, Dyxin, LMCD1
Gene Name
LMCD1
UniProt
Q9NZU5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.
Clonality
Polyclonal
Tissue Specificity
Expressed in the heart (at protein level) . Expressed in many tissues with highest abundance in skeletal muscle
Applications
WB
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
Function
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6- mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity) . Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Molecular Weight
40833 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
Cytoplasm. Nucleus. Note=May shuttle between the cytoplasm and the nucleus.

Frequently Asked Questions

What is the catalog number for Anti-LMCD1 Antibody (C-term)?

The catalog number for Anti-LMCD1 Antibody (C-term) is A08888.

Is Anti-LMCD1 Antibody (C-term) in stock?

Anti-LMCD1 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-LMCD1 Antibody (C-term)?

The safety data sheet for Anti-LMCD1 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A08888.

What is Anti-LMCD1 Antibody (C-term) used for?

Boster Bio Anti-LMCD1 Antibody (C-term) (Catalog # A08888) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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