Anti-IL1RL2 Antibody (Center)

Catalog number A09203-1-01

Discontinued

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About this product

Boster Bio Anti-IL1RL2 Antibody (Center) (Catalog # A09203-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number: A09203-1-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq].
Synonyms: Interleukin-1 receptor-like 2, IL-36 receptor, IL-36R, Interleukin-1 receptor-related protein 2, IL-1Rrp2, IL1R-rp2, IL1RL2, IL1RRP2
Gene Name: IL1RL2
UniProt: Q9HB29
Host: Rabbit
Reactivity: Human
Immunogen: This IL1RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-286 amino acids from the Central region of human IL1RL2.
Clonality: Polyclonal
Tissue Specificity: Expressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte-derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level.
Applications: WB, Flow Cytometry
Field of Research: Immunology, Inflammation, Innate Immunity
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Receptor for interleukin-36 (IL36A, IL36B and IL36G) . After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36- dependent activation of NF-kappa-B, MAPK and other pathways (By similarity) . The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
Molecular Weight: 65405 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Membrane; Single-pass type I membrane protein

Frequently Asked Questions

What is the catalog number for Anti-IL1RL2 Antibody (Center)?

The catalog number for Anti-IL1RL2 Antibody (Center) is A09203-1.

Is Anti-IL1RL2 Antibody (Center) in stock?

Anti-IL1RL2 Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-IL1RL2 Antibody (Center)?

The safety data sheet for Anti-IL1RL2 Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A09203-1.

What is Anti-IL1RL2 Antibody (Center) used for?

Boster Bio Anti-IL1RL2 Antibody (Center) (Catalog # A09203-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.