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Product details

Anti-POU6F2 Antibody (N-term)

Catalog number A10673-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-POU6F2 Antibody (N-term) (Catalog # A10673) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number
A10673-01
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Synonyms
POU domain, class 6, transcription factor 2, Retina-derived POU domain factor 1, RPF-1, POU6F2, RPF1
Gene Name
POU6F2
UniProt
P78424
Host
Rabbit
Reactivity
Human
Immunogen
This POU6F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human POU6F2.
Clonality
Polyclonal
Tissue Specificity
Expressed only within the CNS, where its expression is restricted to the medical habenulla, to a dispersed population of neurons in the dorsal hypothalamus, and to subsets of ganglion and amacrine cells in the retina.
Applications
WB
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
Function
Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA.
Molecular Weight
73265 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
Nucleus.

Frequently Asked Questions

What is the catalog number for Anti-POU6F2 Antibody (N-term)?

The catalog number for Anti-POU6F2 Antibody (N-term) is A10673.

Is Anti-POU6F2 Antibody (N-term) in stock?

Anti-POU6F2 Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-POU6F2 Antibody (N-term)?

The safety data sheet for Anti-POU6F2 Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=A10673.

What is Anti-POU6F2 Antibody (N-term) used for?

Boster Bio Anti-POU6F2 Antibody (N-term) (Catalog # A10673) . Tested in WB application (s) . This antibody reacts with Human.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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