Anti-GSG2 Antibody (Center) — image 1 of 2

Product details

Anti-GSG2 Antibody (Center)

Catalog number A31862-1-01

Discontinued

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About this product

Boster Bio Anti-GSG2 Antibody (Center) (Catalog # A31862-1) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A31862-1-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Post-translational modifications of conserved N-terminal tail residues in histones regulate many aspects of chromosome activity. Mitotic phosphorylation of H3 Thr 3 occurs in prophase and dephosphorylation during anaphase. Haspin, a dual serine/threonine kinase, plays an important role in regulation of chromosome and spindle function during mitosis and meiosis via its function in phosphorylation of the threonine residue in the third position of histone 3 (Thr3) .
Synonyms: Serine/threonine-protein kinase haspin, Germ cell-specific gene 2 protein, H-haspin, Haploid germ cell-specific nuclear protein kinase, GSG2
Gene Name: HASPIN
UniProt: Q8TF76
Host: Rabbit
Reactivity: Human
Immunogen: This Haspin GSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323~352 amino acids from the central region of human haspin.
Clonality: Polyclonal
Tissue Specificity: Strongly expressed in testis. Also present in thymus and bone marrow and low levels observed in prostate, intestine, lung, spleen and lymph node. Expressed in fetal skin, liver, kidney and small intestine and also in proliferating but not non-proliferating cell lines.
Applications: IHC-P, WB
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
Molecular Weight: 88495 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle. Note=Nuclear during interphase and associates with the chromosomes and spindle apparatus during mitosis

Frequently Asked Questions

What is the catalog number for Anti-GSG2 Antibody (Center)?

The catalog number for Anti-GSG2 Antibody (Center) is A31862-1.

Is Anti-GSG2 Antibody (Center) in stock?

Anti-GSG2 Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-GSG2 Antibody (Center)?

The safety data sheet for Anti-GSG2 Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A31862-1.

What is Anti-GSG2 Antibody (Center) used for?

Boster Bio Anti-GSG2 Antibody (Center) (Catalog # A31862-1) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.