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Product details

Anti-SOX2 Antibody

Catalog number M00105-3-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-SOX2 Antibody (Catalog # M00105-3) . Tested in WB, IF, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number
M00105-3-01
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT) .
Synonyms
Transcription factor SOX-2, SOX2
Gene Name
SOX2
UniProt
P48431
Host
Mouse
Reactivity
Human
Immunogen
SOX2 recombinant protein is used to produce this monoclonal antibody.
Clonality
Monoclonal
Clone
Clone: 57CT23.3.4
Applications
WB, IF, Flow Cytometry, IHC-P
Field of Research
Developmental Biology, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
18035408
Molecular Weight
34310 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
IgG1
Subcellular Location
Nucleus speckle {ECO:0000250|UniProtKB:Q05066}. Cytoplasm {ECO:0000250|UniProtKB:Q05738}. Nucleus {ECO:0000250|UniProtKB:Q05738}. Note=Acetylation contributes to its nuclear localization and deacetylation by HDAC3 induces a cytoplasmic delocalization (By similarity) . Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH) (By similarity) Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus (By similarity) . Nuclear import is facilitated by XPO4, a protein that usually acts as a nuclear export signal receptor (By similarity) {ECO:0000250|UniProtKB:Q05066, ECO:0000250|UniProtKB:Q05738}

Frequently Asked Questions

What is the catalog number for Anti-SOX2 Antibody?

The catalog number for Anti-SOX2 Antibody is M00105-3.

Is Anti-SOX2 Antibody in stock?

Anti-SOX2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-SOX2 Antibody?

The safety data sheet for Anti-SOX2 Antibody is available here: https://www.bosterbio.com/msds?sku=M00105-3.

What is Anti-SOX2 Antibody used for?

Boster Bio Anti-SOX2 Antibody (Catalog # M00105-3) . Tested in WB, IF, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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