Anti-IF4E Antibody

Catalog number M00135-2-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-IF4E Antibody (Catalog # M00135-2) . Tested in WB, IF application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: M00135-2-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
Synonyms: Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein, EIF4E, EIF4EL1, EIF4F
Gene Name: EIF4E
UniProt: P06730
Host: Mouse
Reactivity: Human, Mouse, Rat
Immunogen: This IF4E antibody is generated from a mouse immunized with a recombinant protein of human IF4E.
Clonality: Monoclonal
Clone: Clone: 1504CT774.14.55
Applications: WB, IF
Field of Research: Viral process, Host-Virus Interaction
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: 116062002433528529987188226840102257881316271312225788132998718824335285243352852347107822684010
Molecular Weight: 25097 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: IgG1, Κ
Subcellular Location: Cytoplasm, P-body. Cytoplasm. Cytoplasm, Stress granule. Nucleus. Nucleus speckle. Nucleus, nuclear body Note=Interaction with EIF4ENIF1/4E-T is required for localization to processing bodies (P-bodies) (PubMed:16157702, PubMed:24335285, PubMed:25923732) . Imported in the nucleus via interaction with EIF4ENIF1/4E-T via a piggy-back mechanism (PubMed:10856257) Sequestered in the nucleus by EIF4EBP1 and EIF4EBP2 (By similarity) {ECO:0000250|UniProtKB:P63073, ECO:0000269|PubMed:10856257, ECO:0000269|PubMed:16157702, ECO:0000269|PubMed:24335285, ECO:0000269|PubMed:25923732}

Frequently Asked Questions

What is the catalog number for Anti-IF4E Antibody?

The catalog number for Anti-IF4E Antibody is M00135-2.

Is Anti-IF4E Antibody in stock?

Anti-IF4E Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-IF4E Antibody?

The safety data sheet for Anti-IF4E Antibody is available here: https://www.bosterbio.com/msds?sku=M00135-2.

What is Anti-IF4E Antibody used for?

Boster Bio Anti-IF4E Antibody (Catalog # M00135-2) . Tested in WB, IF application (s) . This antibody reacts with Human, Mouse, Rat.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.