Anti-PLCG1 Antibody (Center)

About this product

Boster Bio Anti-PLCG1 Antibody (Center) (Catalog # M00677-1) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number

M00677-1-01

Size / count

80 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.

Synonyms

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, PLC-148, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, PLC-II, Phospholipase C-gamma-1, PLC-gamma-1, PLCG1, PLC1

Gene Name

PLCG1

UniProt

P19174

Host

Rabbit

Reactivity

Human

Immunogen

This PLCG1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 456-488 amino acids from the Central region of human PLCG1.

Clonality

Polyclonal

Applications

WB

Field of Research

Cancer, Cardiovascular, Metabolism, Signal Transduction, Viral process, Host-Virus Interaction, T Cells, Inflammation

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Dilution

WB: 1:2000

Function

17229814

Molecular Weight

148532 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

Rabbit IgG

Subcellular Location

Cell projection, lamellipodium. Cell projection, ruffle. Note=Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.