Product details

Anti-PRKAA2 Antibody

Catalog number M01420-01

Discontinued

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Size / count 80 µL

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About this product

Boster Bio Anti-PRKAA2 Antibody (Catalog # M01420) . Tested in IF, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: M01420-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Synonyms: 5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, PRKAA2, AMPK, AMPK2
Gene Name: PRKAA2
UniProt: P54646
Host: Mouse
Reactivity: Human
Immunogen: This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.
Clonality: Monoclonal
Clone: Clone: 206CT5.4.2
Applications: IF, WB
Field of Research: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Autophagy
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: 1730797117712357173079711771235717307971177123577959015340777572568757111554766115186991586617117711846181849301465184920160076212056413673262437079666212056412856106632029622174860971251974520074060
Molecular Weight: 62320 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: IgG2a, K
Subcellular Location: Cytoplasm {ECO:0000250|UniProtKB:Q8BRK8}. Nucleus. Note=In response to stress, recruited by p53/TP53 to specific promoters.

Frequently Asked Questions

What is the catalog number for Anti-PRKAA2 Antibody?

The catalog number for Anti-PRKAA2 Antibody is M01420.

Is Anti-PRKAA2 Antibody in stock?

Anti-PRKAA2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PRKAA2 Antibody?

The safety data sheet for Anti-PRKAA2 Antibody is available here: https://www.bosterbio.com/msds?sku=M01420.

What is Anti-PRKAA2 Antibody used for?

Boster Bio Anti-PRKAA2 Antibody (Catalog # M01420) . Tested in IF, WB application (s) . This antibody reacts with Human.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.