Anti-WWP2 Antibody (N-term)

Catalog number M03634-01

Discontinued

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About this product

Boster Bio Anti-WWP2 Antibody (N-term) (Catalog # M03634) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: M03634-01
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation- induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
Synonyms: NEDD4-like E3 ubiquitin-protein ligase WWP2, 632-, Atrophin-1-interacting protein 2, AIP2, WW domain-containing protein 2, WWP2
Gene Name: WWP2
UniProt: O00308
Host: Rabbit
Reactivity: Human
Immunogen: This WWP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 218-252 amino acids from the N-terminal region of human WWP2.
Clonality: Polyclonal
Tissue Specificity: Detected in heart, throughout the brain, placenta, lung, liver, muscle, kidney and pancreas. Also detected in spleen and peripheral blood leukocytes.
Applications: WB
Field of Research: Viral process, Host-Virus Interaction
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution: WB: 1:1000
Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T- cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
Molecular Weight: 98912 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: Nucleus

Frequently Asked Questions

What is the catalog number for Anti-WWP2 Antibody (N-term)?

The catalog number for Anti-WWP2 Antibody (N-term) is M03634.

Is Anti-WWP2 Antibody (N-term) in stock?

Anti-WWP2 Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-WWP2 Antibody (N-term)?

The safety data sheet for Anti-WWP2 Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=M03634.

What is Anti-WWP2 Antibody (N-term) used for?

Boster Bio Anti-WWP2 Antibody (N-term) (Catalog # M03634) . Tested in WB application (s) . This antibody reacts with Human.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.