PE/Cyanine5.5 Anti-Mouse CD122 Antibody

About this product

This is a PE/Cyanine5.5 Anti-Mouse CD122 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Specifications

Catalog number

RD20475F-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

Synonyms

Interleukin-2 receptor subunit beta, Il2rb, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, CD122

Gene ID

16185

Swiss Prot

P16297

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

PE/Cyanine5.5

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

0.2 mg/mL

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Rat

Isotype

Rat IgG2a, κ