AF488 Anti-Rat CD8a Antibody

About this product

This is a AF488 Anti-Rat CD8a Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Specifications

Catalog number

RD21173F-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting) . CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck) .

Synonyms

T-cell surface glycoprotein CD8 alpha chain, CD8A, T-lymphocyte differentiation antigen T8/Leu-2, MAL

Gene ID

24930

Swiss Prot

P07725

Reactivity

Rat

Clonality

Monoclonal

Conjugation

AF488

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

0.5 mg/mL

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Mouse

Isotype

Mouse IgG1, κ