Purified Anti-Mouse CD119 Antibody

About this product

This is a Purified Anti-Mouse CD119 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Specifications

Catalog number

RD21412F-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Synonyms

Interferon gamma receptor 1, Ifngr1, IFN-gamma-R1, IFN-gamma-R-alpha, CD119

Gene ID

15979

Swiss Prot

P15261

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

0.5 mg/mL

Buffer

PBS with 0.05% Proclin300

Storage Conditions

Store at 2~8°C. Do not freeze.

Host or Source

Rat

Isotype

Rat IgG2a, κ