PerCP/Cyanine5.5 Anti-Mouse CD49b Antibody

About this product

This is a PerCP/Cyanine5.5 Anti-Mouse CD49b Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Specifications

Catalog number

RD21437F-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection) . DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

Synonyms

Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b

Gene ID

16398

Swiss Prot

Q62469

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

PerCP/Cyanine5.5

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

0.2 mg/mL

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Rat

Isotype

Rat IgM, κ