Purified Anti-Mouse CD279/PD-1 Antibody

About this product

This is a Purified Anti-Mouse CD279/PD-1 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Specifications

Catalog number

RD21638F-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2) . It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Synonyms

PD-1, Programmed Death-1

Gene ID

18566

Swiss Prot

Q02242

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

0.5 mg/mL

Buffer

PBS with 0.05% Proclin300

Storage Conditions

Store at 2~8°C. Do not freeze.

Host or Source

Rat

Isotype

Rat IgG2a, κ