AFViolet 450 Anti-Mouse CD80 Antibody

About this product

This is a AFViolet 450 Anti-Mouse CD80 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Specifications

Catalog number

RD30111F-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Synonyms

T-lymphocyte activation antigen CD80, Cd80, Activation B7-1 antigen, B7

Gene ID

12519

Swiss Prot

Q00609

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

AFViolet 450

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

0.5 mg/mL

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Armenian Hamster

Isotype

Armenian Hamster IgG