PE/Cyanine7 Anti-Human/Mouse KLRG-1 Antibody

About this product

This is a PE/Cyanine7 Anti-Human/Mouse KLRG-1 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Specifications

Catalog number

RD30512F-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag) . KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG25 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

Synonyms

MAFA, 2F25-Ag

Gene ID

10219 ,50928

Swiss Prot

Q96E93, O88713

Reactivity

Human, Mouse

Clonality

Monoclonal

Conjugation

PE/Cyanine7

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

0.2 mg/mL

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Syrian Hamster

Isotype

Syrian Hamster IgG