APC Anti-Mouse CD34 Antibody

Catalog number RD30531F-01

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Price for RD30531F-01

Size / count 25 µg

About this product

This is a APC Anti-Mouse CD34 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Specifications

Catalog number: RD30531F-01
Size / count: 25 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: The RAM34 antibody reacts with the CD34 glycoprotein on the surface of three independently derived mouse CD34-transfected cell lines. RAM34 antibody also reacts with the mouse cell lines PA6, 416B, Swiss 3T6, NIH, 3T3, DA1, and M1, all of which are positive for expression of mouse CD34 mRNA. Cell lines shown to be negative for CD34 transcript, including WEHI-3B, EL4, 18.8, and CMT64/61, are also negative for surface expression of CD34 as determined by RAM34 staining. Normal thymocytes and splenocytes are negative for CD34 expression. In the bone marrow, 7-10% of cells are stained with RAM34 mAb, including most of the Ly-6A/E (Sca-1) + CD90 (Thy-1) low Lineage Marker- hematopoietic stem cell-enriched subpopulation and myeloerythroid progenitors. CD34 is also expressed on a small percentage of fetal liver cells, including NK-cell progenitors. CD34 has been reported to be expressed on the endothelium of capillaries and, in this form, to function as a ligand for L-selectin. Consistent with this observation, RAM34 antibody stains endothelial cells in spleen, thymus, and postcapillary HEVs in the lymph nodes. It is reported that RAM34 antibody can be used to select CD34+ CD117 (c-Kit) + Ly-6A/E (Sca-1) + Lineage Marker- bone marrow-derived hematopoietic stem cells, capable of short-term multi-lineage reconstitution of lethally irradiated mice; while the CD34- CD117+ Sca-1+ Lineage Marker- population contains self-renewing hematopoietic stem cells. Similarly, the bone marrow population with high dye-efflux capacity and which is highly enriched for long-term reconstituting hematopoietic stem cells is CD34- CD117 (c-Kit) + Ly-6A/E (Sca-1) + Lineage Marker-.
Synonyms: Hematopoietic progenitor cell antigen CD34
Gene ID: 12490
Swiss Prot: Q64314
Reactivity: Mouse
Clonality: Monoclonal
Conjugation: APC
Type: Flow Cytometry Antibody
Applications: FC
Assay Type: Antibody
Concentration: 0.2 mg/mL
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage Conditions: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Host or Source: Rat
Isotype: Rat IgG2a, κ

Frequently Asked Questions

What is the catalog number for APC Anti-Mouse CD34 Antibody?

The catalog number for APC Anti-Mouse CD34 Antibody is RD30531F.

What sizes are available for APC Anti-Mouse CD34 Antibody?

APC Anti-Mouse CD34 Antibody is available in the following size(s): 25 µg, 100 µg.

How many pack sizes does APC Anti-Mouse CD34 Antibody come in?

APC Anti-Mouse CD34 Antibody is available in 2 different pack sizes.

Is APC Anti-Mouse CD34 Antibody in stock?

APC Anti-Mouse CD34 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is APC Anti-Mouse CD34 Antibody used for?

This is a APC Anti-Mouse CD34 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.