GITR Recombinant Rabbit Monoclonal Antibody [PSH04-06]

Catalog number HA722087

Price for HA722087

Size / count 100 µL

About this product

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also known as glucocorticoid-induced TNFR-related protein (GITR) or CD357. GITR is encoded and tnfrsf18 gene at chromosome 4 in mice. GITR is type I transmembrane protein and is described in 4 different isoforms. GITR human orthologue, also called activation-inducible TNFR family receptor (AITR), is encoded by the TNFRSF18 gene at chromosome 1. GITR is a member of TNFR superfamily and shares high homology in cytoplasmic domain, characterized with cysteine pseudo-repeats, with other members of TNFRSF, such as CD137, OX40 or CD27. GITR is constitutively expressed on CD25+CD4+ regulatory T cells and its expression is upregulated on all T cell subsets after activation. GITR is also expressed on murine neutrophils and NK cells. GITR interacts with its ligand (GITRL) that is expressed on antigen-presenting cells (APC) and endothelial cells.

Specifications

Catalog number: HA722087
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Activation inducible TNFR family receptor antibody Activation-inducible TNFR family receptor antibody AITR antibody CD357 antibody GITR antibody GITR D antibody GITR-D antibody GITRD antibody Glucocorticoid induced TNFR related protein antibody glucocorticoid-induced tnf receptor ligand antibody glucocorticoid-induced tnf receptors ligand antibody Glucocorticoid-induced TNFR-related protein antibody TNF receptor superfamily activation inducible protein antibody TNFRSF 18 antibody TNFRSF18 antibody TNR18_HUMAN antibody Tumor necrosis factor receptor superfamily member 18 antibody Tumor necrosis factor receptor superfamily member 18 precursor antibody
Abbreviation: TNFRSF18, AITR, GITR
Swiss Prot: Q9Y5U5 Human
Cellular Locus: Cell membrane; Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human GITR aa 1-162 / 241.
Isotype: IgG
Clone: PSH04-06
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: HUT 102 cell lysates, HUT 102.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:200 ;FC: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 26 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for GITR Recombinant Rabbit Monoclonal Antibody [PSH04-06]?

The catalog number for GITR Recombinant Rabbit Monoclonal Antibody [PSH04-06] is HA722087.

What sizes are available for GITR Recombinant Rabbit Monoclonal Antibody [PSH04-06]?

GITR Recombinant Rabbit Monoclonal Antibody [PSH04-06] is available in the following size(s): 100 µL.

Is GITR Recombinant Rabbit Monoclonal Antibody [PSH04-06] in stock?

GITR Recombinant Rabbit Monoclonal Antibody [PSH04-06] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GITR Recombinant Rabbit Monoclonal Antibody [PSH04-06] used for?

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.