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Product details

NSUN2 Recombinant Rabbit Monoclonal Antibody [PSH05-05]

Catalog number HA722219

Price for HA722219

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Size / count 100 µL

About this product

NOP2/Sun domain family, member 2 is a protein that in humans is encoded by the NSUN2 gene. Alternatively spliced transcript variants encoding different isoforms have been noted for the gene. The protein is a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA (Leu) (CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 is also localized on mitochondria and is capable of introducing post-transcriptional modifications in mitochondrial tRNAs. Mutations in this gene have been found associated to cases of Dubowitz-like syndrome.

Specifications

Catalog number
HA722219
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
5 methycytoisine methyltransferase antibody D13Wsu123e antibody FLJ20303 antibody hTrm4 antibody MISU antibody Myc induced SUN domain containing protein antibody NOL1/NOP2/Sun domain family 2 antibody NOL1/NOP2/Sun domain family 2 protein antibody NOL1/NOP2/Sun domain family member 2 antibody NSUN 2 antibody NSUN2 antibody NSUN2_HUMAN antibody SAKI antibody Substrate of AIM1/Aurora kinase B antibody TRM4 antibody tRNA (cytosine 5 ) methyltransferase antibody tRNA (cytosine 5 ) methyltransferase NSUN2 antibody tRNA (cytosine (34)-C (5))-methyltransferase antibody tRNA (cytosine-5-)-methyltransferase antibody tRNA methyltransferase 4 homolo antibody tRNA methyltransferase 4 homolog antibody
Abbreviation
NSUN2, SAKI, TRM4
Swiss Prot
Q08J23 Human, Q1HFZ0 Mouse,
Cellular Locus
Nucleus, nucleolus, Cytoplasm, Mitochondrion, cytoskeleton, spindle, Secreted, extracellular exosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Monkey
Immunogen
Recombinant protein within human NSUN2 aa1-767.
Isotype
IgG
Clone
PSH05-05
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, IF-Tissue, IP
Positive Control
HeLa cell lysate, HepG2 cell lysate, Jurkat cell lysate, HEK-293 cell lysate, 293T cell lysate, A431 cell lysate, HCT 116 cell lysate, Caco-2 cell lysate, Neuro-2a cell lysate, COS-1 cell lysate, human testis tissue, human small intestine tissue, HeLa.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:250 ;IHC-P: 1:1,000 ;IF-Tissue: 1:200 ;IP: 1-2μg/sample
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 87 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for NSUN2 Recombinant Rabbit Monoclonal Antibody [PSH05-05]?

The catalog number for NSUN2 Recombinant Rabbit Monoclonal Antibody [PSH05-05] is HA722219.

What sizes are available for NSUN2 Recombinant Rabbit Monoclonal Antibody [PSH05-05]?

NSUN2 Recombinant Rabbit Monoclonal Antibody [PSH05-05] is available in the following size(s): 100 µL.

Is NSUN2 Recombinant Rabbit Monoclonal Antibody [PSH05-05] in stock?

NSUN2 Recombinant Rabbit Monoclonal Antibody [PSH05-05] is currently made to order / not held in immediate stock. Contact us for lead time.

What is NSUN2 Recombinant Rabbit Monoclonal Antibody [PSH05-05] used for?

NOP2/Sun domain family, member 2 is a protein that in humans is encoded by the NSUN2 gene. Alternatively spliced transcript variants encoding different isoforms have been noted for the gene. The protein is a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at po

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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