Elab Fluor® Violet 450 Anti-Mouse CD122 Antibody[TM-Beta 1]

Specifications

Catalog number

AN00418Q-01

Size / count

50 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-β1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

Abbreviation

CD122

Gene ID

16185

UniProt

P16297

Host

Rat

Reactivity

Mouse

Target

IL-2 Receptor β chain; IL-2Rβ

Clonality

Monoclonal

Clone

TM-Beta 1

Conjugation

Elab Fluor®Violet 450

Applications

FCM

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Rat IgG2b, κ