FLAP Recombinant Rabbit Monoclonal Antibody [JE39-03]

Catalog number HA722341

Price for HA722341

Size / count 100 µL

About this product

Arachidonate 5-lipoxygenase-activating protein also known as 5-lipoxygenase activating protein, or FLAP, is a protein that in humans is encoded by the ALOX5AP gene. FLAP is necessary for the activation of 5-lipoxygenase and therefore for the production of leukotrienes, 5-hydroxyeicosatetraenoic acid, 5-oxo-eicosatetraenoic acid, and specialized pro-resolving mediators of the lipoxin and resolvin classes. It is an integral protein within the nuclear membrane. FLAP is necessary in synthesis of leukotriene, which are lipid mediators of inflammation that is involved in respiratory and cardiovascular diseases. FLAP functions as a membrane anchor for 5-lipooxygenase and as an amine acid-bind protein. How FLAP activates 5-lipooxygenase is not completely understood, but there is a physical interaction between the two. FLAP structure consists of 4 transmembrane alpha helices, but they are found in trimer forming a barrel. The barrel is about 60 Å high and 36 Å wide.

Specifications

Catalog number: HA722341
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 5-lipoxygenase activating protein antibody AL5AP_HUMAN antibody ALOX 5AP antibody ALOX5 AP antibody ALOX5AP antibody Arachidonate 5 lipoxygenase activating protein antibody Arachidonate 5-lipoxygenase-activating protein antibody Five lipoxygenase activating protein antibody FLAP antibody MK 886 binding protein antibody MK-886-binding protein antibody
Abbreviation: ALOX5AP, FLAP
Swiss Prot: P20292 Human
Cellular Locus: Nucleus membrane, Endoplasmic reticulum membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human FLAP aa 100-161.
Isotype: IgG
Clone: JE39-03
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: U-937 cell lysate, THP-1 cell lysate, THP-1 treated with 50nM TPA overnight then add 5μg/mL LPS for 8 hours cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 18 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for FLAP Recombinant Rabbit Monoclonal Antibody [JE39-03]?

The catalog number for FLAP Recombinant Rabbit Monoclonal Antibody [JE39-03] is HA722341.

What sizes are available for FLAP Recombinant Rabbit Monoclonal Antibody [JE39-03]?

FLAP Recombinant Rabbit Monoclonal Antibody [JE39-03] is available in the following size(s): 100 µL.

Is FLAP Recombinant Rabbit Monoclonal Antibody [JE39-03] in stock?

FLAP Recombinant Rabbit Monoclonal Antibody [JE39-03] is currently made to order / not held in immediate stock. Contact us for lead time.

What is FLAP Recombinant Rabbit Monoclonal Antibody [JE39-03] used for?

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.