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Product details

APP/β-Amyloid Recombinant Rabbit Monoclonal Antibody [JE30-54]

Catalog number HA722139

Price for HA722139

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Size / count 100 µL

About this product

Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions as a cell surface receptor and has been implicated as a regulator of synapse formation, neural plasticity, antimicrobial activity, and iron export. It is coded for by the gene APP and regulated by substrate presentation. APP is best known as the precursor molecule whose proteolysis generates amyloid beta (Aβ), a polypeptide containing 37 to 49 amino acid residues, whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients.

Specifications

Catalog number
HA722139
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
A4 amyloid protein antibody A4_HUMAN antibody AAA antibody ABETA antibody ABPP antibody AD1 antibody AICD-50 antibody AICD-57 antibody AICD-59 antibody AID (50) antibody AID (57) antibody AID (59) antibody Alzheimer disease amyloid protein antibody Amyloid beta (A4) precursor protein antibody Amyloid beta A4 protein antibody Amyloid beta protein antibody Amyloid intracellular domain 50 antibody Amyloid intracellular domain 57 antibody Amyloid intracellular domain 59 antibody Amyloid precursor protein antibody APP antibody APPI antibody Beta-amyloid precursor protein antibody C31 antibody Cerebral vascular amyloid peptide antibody CTFgamma antibody CVAP antibody Gamma-CTF (50) antibody Gamma-CTF (57) antibody Gamma-CTF (59) antibody peptidase nexin II antibody peptidase nexin-II antibody PN 2 antibody PN II antibody PN-II antibody PN2 antibody PreA4 antibody Protease nexin II antibody Protease nexin-II antibody S-APP-alpha antibody S-APP-beta antibody sAPP antibody
Abbreviation
APP, A4, AD1
Swiss Prot
P05067 Human, P12023 Mouse, P08592 Rat
Cellular Locus
Cell membrane, Membrane, Perikaryon, Cell projection, growth cone, clathrin-coated pit, Early endosome, Cytoplasmic vesicle.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Amyloid Precursor Protein aa 671-770 / 770.
Isotype
IgG
Clone
JE30-54
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue, IHC-Fr
Positive Control
PC-3 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, human brain tissue, mouse brain tissue, rat brain tissue, mouse cerebral cortex tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Tissue: 1:200 ;IHC-Fr: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 87 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for APP/β-Amyloid Recombinant Rabbit Monoclonal Antibody [JE30-54]?

The catalog number for APP/β-Amyloid Recombinant Rabbit Monoclonal Antibody [JE30-54] is HA722139.

What sizes are available for APP/β-Amyloid Recombinant Rabbit Monoclonal Antibody [JE30-54]?

APP/β-Amyloid Recombinant Rabbit Monoclonal Antibody [JE30-54] is available in the following size(s): 100 µL.

Is APP/β-Amyloid Recombinant Rabbit Monoclonal Antibody [JE30-54] in stock?

APP/β-Amyloid Recombinant Rabbit Monoclonal Antibody [JE30-54] is currently made to order / not held in immediate stock. Contact us for lead time.

What is APP/β-Amyloid Recombinant Rabbit Monoclonal Antibody [JE30-54] used for?

Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions as a cell surface receptor and has been implicated as a regulator of synapse formation, neural plasticity, antimicrobial activity, and iron export.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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