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Product details

Phospho-Tau (T181) Recombinant Rabbit Monoclonal Antibody [PSH05-42]

Catalog number HA722271

Price for HA722271

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Size / count 100 µL

About this product

The tau proteins (abbreviated from tubulin associated unit are a group of six highly soluble protein isoforms produced by alternative splicing from the gene MAPT (microtubule-associated protein tau). They have roles primarily in maintaining the stability of microtubules in axons and are abundant in the neurons of the central nervous system (CNS), where the cerebral cortex has the highest abundance. They are less common elsewhere but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. Pathologies and dementias of the nervous system such as Alzheimer's disease and Parkinson's disease are associated with tau proteins that have become hyperphosphorylated insoluble aggregates called neurofibrillary tangles. The tau proteins were identified in 1975 as heat-stable proteins essential for microtubule assembly, and since then they have been characterized as intrinsically disordered proteins.

Specifications

Catalog number
HA722271
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
AI413597 antibody AW045860 antibody DDPAC antibody FLJ31424 antibody FTDP 17 antibody G protein beta1/gamma2 subunit interacting factor 1 antibody MAPT antibody MAPTL antibody MGC134287 antibody MGC138549 antibody MGC156663 antibody Microtubule associated protein tau antibody Microtubule associated protein tau isoform 4 antibody Microtubule-associated protein tau antibody MSTD antibody Mtapt antibody MTBT1 antibody MTBT2 antibody Neurofibrillary tangle protein antibody Paired helical filament tau antibody Paired helical filament-tau antibody PHF tau antibody PHF-tau antibody PPND antibody PPP1R103 antibody Protein phosphatase 1, regulatory subunit 103 antibody pTau antibody RNPTAU antibody TAU antibody TAU_HUMAN antibody Tauopathy and respiratory failure antibody Tauopathy and respiratory failure, included antibody
Abbreviation
MAPT, MAPTL, MTBT1, TAU
Swiss Prot
P10636-8 Human, P10637 Mouse
Cellular Locus
Cytoplasm, cytosol, Cell membrane, cytoskeleton, Cell projection, axon, dendrite, Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding T181 of human Tau protein (P10636-8).
Isotype
IgG
Clone
PSH05-42
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Human brain tissue lysate, human brain tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 79 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Phospho-Tau (T181) Recombinant Rabbit Monoclonal Antibody [PSH05-42]?

The catalog number for Phospho-Tau (T181) Recombinant Rabbit Monoclonal Antibody [PSH05-42] is HA722271.

What sizes are available for Phospho-Tau (T181) Recombinant Rabbit Monoclonal Antibody [PSH05-42]?

Phospho-Tau (T181) Recombinant Rabbit Monoclonal Antibody [PSH05-42] is available in the following size(s): 100 µL.

Is Phospho-Tau (T181) Recombinant Rabbit Monoclonal Antibody [PSH05-42] in stock?

Phospho-Tau (T181) Recombinant Rabbit Monoclonal Antibody [PSH05-42] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-Tau (T181) Recombinant Rabbit Monoclonal Antibody [PSH05-42] used for?

The tau proteins (abbreviated from tubulin associated unit are a group of six highly soluble protein isoforms produced by alternative splicing from the gene MAPT (microtubule-associated protein tau). They have roles primarily in maintaining the stability of microtubules in axons and are abundant in

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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