Transcription factor AP-2-alpha Recombinant Rabbit Monoclonal Antibody [PSH02-06]

About this product

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

Specifications

Catalog number

HA721765

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Activating enhancer binding protein 2 alpha antibody Activating enhancer-binding protein 2-alpha antibody Activator protein 2 antibody AP 2 transcription factor antibody AP 2alpha antibody AP-2 antibody AP-2 transcription factor antibody AP2 antibody AP2 Transcription Factor antibody AP2-alpha antibody AP2A_HUMAN antibody AP2TF antibody BOFS antibody FLJ51761 antibody TFAP 2 antibody TFAP 2A antibody TFAP2 antibody TFAP2A antibody Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha) antibody Transcription factor AP-2-alpha antibody Transcription factor AP2 alpha antibody

Abbreviation

TFAP2A, AP2TF, TFAP2

Swiss Prot

P05549 Human

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human TFAP2A aa 1-437 / 437.

Isotype

IgG

Clone

PSH02-06

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

HepG2 cell lysate, SiHa cell lysate, HepG2, human breast tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Cell: 1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 48 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes