AF/LE Purified Anti-Human CD11c Antibody[3.9]

Specifications

Catalog number

E-AB-F14860-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4) . The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

Abbreviation

CD11c

Gene ID

3687

UniProt

P20702

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD11c protein

Target

SLEB; Leukocyte adhesion receptor p150+; ITGAX; CD11C; SLEB6; CD11 antigen-like family member C; Integrin alpha-X; Leukocyte adhesion receptor p150+95; p150-95; CR4; integrin &alpha-X-X

Clonality

Monoclonal

Clone

3.9

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Signal Transduction; Immunology; Stem Cells

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Isotype

Mouse IgG1, κ