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Product details

CASP4 Polyclonal Antibody

Catalog number D-AB-10447L-01

Discontinued

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Price for D-AB-10447L-01

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Size / count 25 µL

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Specifications

Catalog number
D-AB-10447L-01
Size / count
25 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
Abbreviation
CASP4
UniProt
P49662
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant Human CASP4 protein expressed by E.coli
Target
Apoptotic cysteine protease Mih1/TX; CASP-4; CASP4; CASP4; Caspase 4 apoptosis related cysteine peptidase; Caspase-4 subunit 2; Caspase4; ICE (rel) -II; ICE (rel) II; ICEREL II; ICH2; Mih1/TX; Protease ICH-2; Protease TX; TX
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC; IF
Field of Research
Cancer; Cell Biology; Metabolism
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IHC 1:400-1:800; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for CASP4 Polyclonal Antibody?

The catalog number for CASP4 Polyclonal Antibody is D-AB-10447L.

What sizes are available for CASP4 Polyclonal Antibody?

CASP4 Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does CASP4 Polyclonal Antibody come in?

CASP4 Polyclonal Antibody is available in 2 different pack sizes.

Is CASP4 Polyclonal Antibody in stock?

CASP4 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CASP4 Polyclonal Antibody?

CASP4 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CASP4 Polyclonal Antibody?

Estimated delivery time for CASP4 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CASP4 Polyclonal Antibody?

The safety data sheet for CASP4 Polyclonal Antibody is available here: https://789.bio/eb/5VDRZL.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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