Purified Anti-Human CD279 Antibody[5C4.B8 (Nivolumab) ]

Specifications

Catalog number

AN006230P-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Rogrammed Death-1 (PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses . Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or down-regulate T cell activation (CTLA-4 and PD-1) .

Abbreviation

CD279

Gene ID

5133

UniProt

Q15116

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human CD279 protein

Target

SLEB; hSLE; Programmed Death; programmed cell death; Programmed cell death protein; Systemic lupus erythematosus susceptibility; hPD; PDCD1; CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death 1; PD 1; CD279 antigen; hPD 1; hPD l; PDCD 1; Programmed cell death 1 protein; Programmed Death-1; Protein PD 1; Protein PD-1; Systemic lupus erythematosus susceptibility 2; Programmed cell death protein 1; CD279; CD279 antigen; hPD 1; hPD l; hPD-1; hSLE1; PD 1; PD-1; PD1; PDCD 1; PDCD1; PDCD1; Programmed cell death 1; Programmed cell death 1 protein; Programmed cell death protein 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2

Clonality

Monoclonal

Clone

5C4.B8 (Nivolumab)

Conjugation

Unconjugated

Applications

FCM

Field of Research

Cell Biology; Immunology; Cancer

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Rabbit IgG, κ