Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody

Catalog number AN00298L-01

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for AN00298L-01

Size / count 25 µL

Specifications

Catalog number: AN00298L-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Lamin A/C is also named as LMNA, or LMN1. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. The lack of lamin A/C can be as a novel marker for undifferentiated embryonic stem cells and lamin A/C expression is as an early indicator of differentiation (PMID: 16179429) . Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. This protein has 4 isoforms produced by alternative splicing with the molecular weight of 74 kDa,65 kDa,70 kDa and 64 kDa. This antibody can recognize 4 isoforms of Lamin A/C.
Abbreviation: Lamin A/C
UniProt: P02545
Host: Mouse
Reactivity: Human
Immunogen: Recombinant Human Lamin A/C protein expressed by E.coli
Target: Prelamin-A/C; LMNA; LMN1; Lamin A/C
Clonality: Monoclonal
Clone: 4F1
Conjugation: Elab Fluor®488
Applications: IF
Field of Research: Signal Transduction; Tags and Cell Markers; Cancer; Cell Biology; Developmental Biology; Epigenetics and Nuclear Signaling; Biochemicals
Purification: Protein A/G Purification
Concentration: 1 mg/mL
Dilution: IF 1:100-1:200
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.
Isotype: IgG1

Frequently Asked Questions

What is the catalog number for Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody?

The catalog number for Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody is AN00298L.

What sizes are available for Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody?

Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody come in?

Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody is available in 2 different pack sizes.

Is Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody in stock?

Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody?

Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody?

Estimated delivery time for Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody?

The safety data sheet for Elab Fluor® 488-conjugated Lamin A/C Monoclonal Antibody is available here: https://789.bio/eb/pmmPh5.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.