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Product details

Purified Anti-Human CD192 Antibody[K036C2]

Catalog number E-AB-F1385A-01

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Price for E-AB-F1385A-01

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Size / count 25 µg

Specifications

Catalog number
E-AB-F1385A-01
Size / count
25 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
CCR2 is a chemokine receptor that binds monocyte chemoattractant proteins (MCP-1, 2, 3 and 4) . Two spliced variants were initially described for CCR2 (CCR2A and CCR2B) . These variants differ in their terminal carboxyl tails. Monocyte adhesion to the arterial endothelium and subsequent migration into the intima are central events in the pathogenesis of atherosclerosis. CCR2 and MCP-1 have been associated to atherosclerotic plaques. MCP-1 is induced by modified-LDL in endothelial cells and may trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Local overexpression of MCP-1 at vessel walls induces infiltration of macrophages and formation of atherosclerotic lesions. Obesity induces an inflammatory state that is implicated in many clinically important complications, including insulin resistance, diabetes, atherosclerosis, and non-alcoholic fatty liver disease. CCR2 influences the development of obesity and associated adipose tissue inflammation.
Abbreviation
CD192
Gene ID
729230
UniProt
P41597
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD192 protein
Target
CKR; CMKBR; CC-CKR; CCR; CCR2; CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R; FLJ78302; C C chemokine receptor type 2; C C CKR 2; CC chemokine receptor type 2; C-C chemokine receptor type 2; CC CKR 2; C-C CKR-2; CCCKR2; CCR 2; CCR1L; CCR5L; CD192 antigen; Chemokine C C motif receptor 2; Chemokine CC Motif Receptor 2; CKR 2; cluster of differentiation 192; MCP 1 R; MCP1 RECEPTOR; MCP1R; MCP-1-R; Monocyte chemoattractant protein 1 receptor; Monocyte Chemotactic Protein 1 Receptor
Clonality
Monoclonal
Clone
K036C2
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Microbiology; Signal Transduction; Cancer; Cardiovascular
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Mouse IgG2a, κ

Frequently Asked Questions

What is the catalog number for Purified Anti-Human CD192 Antibody[K036C2]?

The catalog number for Purified Anti-Human CD192 Antibody[K036C2] is E-AB-F1385A.

What sizes are available for Purified Anti-Human CD192 Antibody[K036C2]?

Purified Anti-Human CD192 Antibody[K036C2] is available in the following size(s): 25 µg, 100 µg.

How many pack sizes does Purified Anti-Human CD192 Antibody[K036C2] come in?

Purified Anti-Human CD192 Antibody[K036C2] is available in 2 different pack sizes.

Is Purified Anti-Human CD192 Antibody[K036C2] in stock?

Purified Anti-Human CD192 Antibody[K036C2] is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Purified Anti-Human CD192 Antibody[K036C2]?

Purified Anti-Human CD192 Antibody[K036C2] is manufactured by Elabscience.

What is the estimated delivery time for Purified Anti-Human CD192 Antibody[K036C2]?

Estimated delivery time for Purified Anti-Human CD192 Antibody[K036C2] is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Purified Anti-Human CD192 Antibody[K036C2]?

The safety data sheet for Purified Anti-Human CD192 Antibody[K036C2] is available here: https://789.bio/eb/LteiaL.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

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