Mouse AGO2 Protein, His Tag

About this product

Mouse AGO2 Protein, His Tag (AG2-M5543) is expressed from Baculovirus-Insect cells. It contains AA Tyr 2 - Ala 860 (Accession # Q8CJG0-1) .

Specifications

Catalog number

AG2-M5543-1mg

Size / count

1 mg

Dry ice

Yes

Hazardous

No

Discontinued

Yes

Background

This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific) . The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 99.2 kDa. The protein migrates as 95-110 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q8CJG0-1

Expression Region

Tyr 2 - Ala 860

Host

Insect Cells

Target

AGO2

Conjugation

Unconjugated

Tag

N-10xHis

Stability

● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Liquid

Buffer

PBS, pH7.4

Additives

Glycerol

Molecular Weight

99.2 kDa

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

1mg*1

Species

Mouse