PDGFR alpha Recombinant Rabbit monoclonal Antibody [JF104-6]

Catalog number ET1702-49-50UL

Price for ET1702-49-50UL

Size / count 50 µL

About this product

Platelet-derived growth factor (PDGF) is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PGDF-AA, PDGF-AB and PDGF-BB. These three isoforms bind with different affinities to two receptor types, PDGFR-α and -β, which are endowed with protein tyrosine kinase domains. PDGFR-α can bind to both A and B subunits of PDGF, while PDGFR-β can only bind the B subunit. Ligand binding promotes either homo- or heterodimerization of the PDGF receptors in a specific manner. PDGF-AA induces the dimerization of two α receptors, PDGF-AB induces dimerization of αα and αβ and PDGF-BB induces the formation of three types of dimers, αα, αβ and ββ. Translocation of the PDGFR-β gene with the Tel gene is linked to chronic myelomonocytic leukemia (CMML), a myelodysplastic syndrome, and demonstrates the oncogenic potential of the PDGF receptors.

Specifications

Catalog number: ET1702-49-50UL
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Alpha-type platelet-derived growth factor receptor antibody CD140 antigen-like family member A antibody CD140a antibody CD140a antigen antibody MGC74795 antibody PDGF alpha chain antibody PDGF-R-alpha antibody PDGFR 2 antibody PDGFR alpha antibody PDGFR2 antibody PDGFRA antibody PDGFRA/BCR fusion antibody PGFRA_HUMAN antibody Platelet derived growth factor receptor 2 antibody Platelet derived growth factor receptor alpha antibody Platelet derived growth factor receptor alpha polypeptide antibody Platelet derived growth factor receptor antibody Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein antibody RHEPDGFRA antibody
Abbreviation: PDGFR-alpha, PDGFR-2, PDGFRA
Swiss Prot: P16234 Human, P26618 Mouse, P20786 Rat
Cellular Locus: Golgi apparatus, Cell membrane, cilium.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within C-terminal human PDGFR alpha.
Isotype: IgG
Clone: JF104-6
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, FC, IHC-Fr
Positive Control: Mouse embryonic femur tissue, mouse embryonic intervertebral disc tissue, mouse embryonic lung tissue, rat embryonic femur tissue, rat embryonic intervertebral disc tissue, rat embryonic lung tissue, rat endometrium tissue, human colon tissue, human colon cancer tissue, human glioblastoma tissue, NIH/3T3 cell lysates, SHG-44 cell lysates, A549, NIH/3T3.
Concentration: 1 mg/mL
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 123 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for PDGFR alpha Recombinant Rabbit monoclonal Antibody [JF104-6]?

The catalog number for PDGFR alpha Recombinant Rabbit monoclonal Antibody [JF104-6] is ET1702-49-50UL.

What sizes are available for PDGFR alpha Recombinant Rabbit monoclonal Antibody [JF104-6]?

PDGFR alpha Recombinant Rabbit monoclonal Antibody [JF104-6] is available in the following size(s): 50 µL.

Is PDGFR alpha Recombinant Rabbit monoclonal Antibody [JF104-6] in stock?

PDGFR alpha Recombinant Rabbit monoclonal Antibody [JF104-6] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PDGFR alpha Recombinant Rabbit monoclonal Antibody [JF104-6] used for?

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.