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![N4BP1 Recombinant Rabbit Monoclonal Antibody [JE63-75] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8e061270361ea82447/imageurl/ha722576.webp)
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Product details
Catalog number HA722576
Price for HA722576
Size / count 100 µL
Potent suppressor of cytokine production that acts as a regulator of innate immune signaling and inflammation. Acts as a key negative regulator of select cytokine and chemokine responses elicited by TRIF-independent Toll-like receptors (TLRs), thereby limiting inflammatory cytokine responses to minor insults. In response to more threatening pathogens, cleaved by CASP8 downstream of TLR3 or TLR4, leading to its inactivation, thereby allowing production of inflammatory cytokines (By similarity). Acts as a restriction factor against some viruses, such as HIV-1: restricts HIV-1 replication by binding to HIV-1 mRNAs and mediating their degradation via its ribonuclease activity. Also acts as an inhibitor of the E3 ubiquitin-protein ligase ITCH: acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity).
The catalog number for N4BP1 Recombinant Rabbit Monoclonal Antibody [JE63-75] is HA722576.
N4BP1 Recombinant Rabbit Monoclonal Antibody [JE63-75] is available in the following size(s): 100 µL.
N4BP1 Recombinant Rabbit Monoclonal Antibody [JE63-75] is currently made to order / not held in immediate stock. Contact us for lead time.
Potent suppressor of cytokine production that acts as a regulator of innate immune signaling and inflammation. Acts as a key negative regulator of select cytokine and chemokine responses elicited by TRIF-independent Toll-like receptors (TLRs), thereby limiting inflammatory cytokine responses to mino
Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.
A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.
Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.
