AF/LE Purified Anti-Human CD122 Antibody[TU27]

Specifications

Catalog number

E-AB-F11510-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains and the intermediate affinity complex comprising heterodimers of the beta and gamma chains. Individual beta chains and alpha chains exhibit low affinity IL-2 binding, and the gamma chain alone does not bind IL-2. In addition to their involvement in IL-2 mediated signal transduction, both the beta chain and gamma chain have been shown to be required for IL-15 mediated signaling. IL-2 R beta is a member of the cytokine receptor superfamily.

Abbreviation

CD122

Gene ID

3560

UniProt

P14784

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD122 protein

Target

P70; IL2RB; CD122; IL15RB; P70-75; IL-2Rβ; p75; IL-2RB; Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; High affinity IL-2 receptor subunit beta; Interleukin-15 receptor subunit beta; p70-75 (p75) ; IL-2Rβ CD122 antigen; High affinity IL 2 receptor beta subunit; High affinity IL 2 receptor subunit beta; IL2 receptor; Interleukin 2 receptor beta; interleukin 2 receptor subunit beta; P70 75; P7075

Clonality

Monoclonal

Clone

TU27

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology; Signal Transduction; Stem Cells

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Isotype

Mouse IgG1, κ