Recombinant Bcl-2 Monoclonal Antibody

Catalog number AN300032P

Discontinued

Price for AN300032P

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

Specifications

Catalog number: AN300032P
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Bcl-2 is a member of a family of proteins that regulates outer mitochondrial membrane permeability. Bcl-2 is an anti-apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Bcl-2 is present on the outer mitochondrial membrane and is also found on other membranes in some cell types. Natural Bcl-2 contains a carboxyl-terminal mitochondria targeting sequence. Recombinant Bcl-2, missing the mitochondrial targeting sequence, maintains its ability to neutralize pro-apoptotic Bcl-2 family members. Neutralization by Bcl-2 appears to be through binding the BH3 region of pro-apoptotic Bcl-2 family members. This activity does not require the mitochondrial targeting sequence.
Abbreviation: BCL2
UniProt: P10415
Host: Rabbit
Reactivity: Human
Immunogen: A synthetic peptide corresponding to the N-terminus of the Human Bcl-2.
Target: B-cell Lymphoma; PPP1R; BCL; Bcl-2; PPP1R50; BCL2; apoptosis regulator Bcl-2; B-cell Lymphoma 2; apoptosis regulator Bcl-2; Bcl-2; PPP1R50; Apoptosis regulator Bcl 2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; B-cell; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma; Oncogene B-cell leukemia 2; Protein phosphatase 1; regulatory subunit 50; Bcl2
Clonality: Monoclonal
Clone: 8D4
Conjugation: Unconjugated
Applications: IHC-P; FCM
Field of Research: Cell Biology; Signal Transduction; Cancer; Kits; Lysates; Other; Metabolism
Purification: Protein A
Concentration: 1 mg/mL
Dilution: IHC-P 1:250-1:1000; FCM 1:25-1:100
Buffer: 0.2 μm filtered solution in PBS
Shipping Conditions: Ice bag
Storage Conditions: This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant Bcl-2 Monoclonal Antibody?

The catalog number for Recombinant Bcl-2 Monoclonal Antibody is AN300032P.

What sizes are available for Recombinant Bcl-2 Monoclonal Antibody?

Recombinant Bcl-2 Monoclonal Antibody is available in the following size(s): 100 µL.

Is Recombinant Bcl-2 Monoclonal Antibody in stock?

Recombinant Bcl-2 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Bcl-2 Monoclonal Antibody?

Recombinant Bcl-2 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Bcl-2 Monoclonal Antibody?

Estimated delivery time for Recombinant Bcl-2 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Bcl-2 Monoclonal Antibody?

The safety data sheet for Recombinant Bcl-2 Monoclonal Antibody is available here: https://789.bio/eb/ktTKYxW0.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.